Endocrine Abstracts

Introduction: It has been seen that Zoledronic acid (ZA) infusion induces an acute inflammatory response associated with rise in inflammatory markers and changes in thyroid function tests resembling non thyroidal illness syndrome. It is also postulated that amino group of ZA has a role in causation of these thyroid function abnormality. (1)Material and methods: An observational study at tertiary care hospital of India where thyroid functions tests were s...

We present here a case of 70 year old female, seen in endocrine clinic for Hypothalamic-Pituitary-Adrenal (HPA) axis suppression after prolonged glucocorticoid use. History revealed that she had prolonged use of prednisolone for her asthma in the past. In 2011, Prednisolone was stopped but she had to be started on Hydrocortisone replacement due to HPA axis suppression. She was taking Hydrocortisone 20 mg BD. Trials to wean her off Hydrocortisone failed due to ongoing tiredness...

Introduction: Raised intracranial pressure is a well-documented complication of obesity in the adult population, but this remains under-recognised in children and young people. The pathophysiology for this association remains unclear, but the complications of raised intracranial pressure can be devastating including potential visual loss. Therefore, the aim of our study was to investigate this link in children and young people.Method: Retrospective data ...

Background: Menopause has been related to a deficiency of bulk and an increment in fat mass. Testosterone treatment is being considered to further develop body organization in menopausal women. Notwithstanding, the portion reaction connections among testosterone and the progressions in body structure and muscle strength in women have not been set up. To decide the portion subordinate impacts of reviewed dosages of testosterone on body arrangement and muscle strength in precise...

Introduction: The aetiology of a diabetic foot ulcer is multifactorial. The three principal components that ascertain the likelihood of ulceration in a diabetic foot are peripheral neuropathy, repeated minor trauma and deformity. Aims:To find the prevalence of diabetes patients having the foot at risk using the Simplified 60-Second Diabetic Foot Screen tool (SSDFST).Objectives: To find out the diabetic foot at risk.1. To ascertain the dispersal of variou...

Introduction: Adrenocortical carcicnoma (ACC) is a rare malignancy with overall incidence of 0.7–2.0 cases/million. It’s a rare & aggressive childhood cancer with a reported incidence of 0.2– 0.3 new cases per 1 million. It has Bimodal distribution - at first decade - 85% functional & 5-6th decade of life 15-30% functional. Paediatric virilising adrenal tumours have a better prognosis after complete resection than in adults. Surgery is the mai...

Background: Etiology of hypopituitarism differs in tropical countries compared to the West and includes pituitary abscess, snake bite, HIV infection, Sheehan syndrome, road traffic accidents, iron overload states etc.Aims and Objectives: The present case series highlights the spectrum of hypopituitarism in tropical countries.Case Details: 1. C1: 23 y/o female presented with loss of consciousness, unrecordable BP and hypoglycemia. H...

Introduction: Thyroid cystic nodules (TCN) are generally due to degenerative changes within colloid nodules or adenomas. True thyroid cysts are uncommon. But the prevalence of malignancy among TCN is controversial since some authors consider it to be low risk while some others consider it to have the same risks as malignancy as the solid lesions of the thyroid. Percutaneous ethanol injection (PEI) is utilised for treating benign cystic thyroid nodules. It is a protected option...

Introduction: There is always been a need for safe and effective adjuvant therapy in type 1 Diabetes not just for glycemic control but also for cardio-renal benefits.Objectives: To evaluate whether addition of DPP-4 inhibitors reduces the ketogenic potential of SGLT2i when used as an adjuvant therapy in type 1 Diabetes.Materials & Methods: 20 type 1 Diabetes subjects above 18 years of age with poorly controlled glycemia (HbA1c ...

Background: The likelihood of developing a fragility fracture rises with age. Osteoarthritis, osteoporosis, and hypovitaminosis D are all extremely common diseases, with 50% of women and 20% of men experiencing a fragility fracture at some point in their lives.Objectives: First, compare the occurrence of osteoporosis, fragility fractures, and risk factors such as low vitamin D levels, low bone mineral density, and the presence of other illnesses that pre...